Literaturbelege

Wirksamkeitsgeprüfte komplementärmedizinische Verfahren in der Fachliteratur:

Arthrose

Selen Lektin Enzym Gemisch

  • Beuth J: Evidence-based complementary ocology. Anticancer Res.30:1767-1771, 2010
  • Uhlenbruck G et al. Reduced side effects of adjuvant hormone therapy in breast cancer patients by complementary medicine. In vivi 24:799-802,2010

CINV

Ingwer

  • S3 Leitlinie Supportivtherapie
  • Ryan JL, Heckler CE, Roscoe J, et al. Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients. Support Care Cancer. 2012;20(7):1479-1489
  • Kim K et al. Major clinical research advances in gynaecologic cancer. J.Gynecol. Oncology 20:203-209, 2009
  • Abdel-Aziz, H., T. Windeck, M. Ploch and E. J. Verspohl (2006). "Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum." Eur J Pharmacol 530(1-2): 136-143. https://www.ncbi.nlm.nih.gov/pubmed/16364290
  • Weimer K, Schulte J, Maichle A, et al. Effects of ginger and expectations on symptoms of nausea in a balanced placebo design. PLoS One. 2012;7(11):e49031.
  • Panahi Y, Saadat A, Sahebkar A, Hashemian F, Taghikhani M, Abolhasani E. Effect of ginger on acute and delayed chemotherapy-induced nausea and vomiting: a pilot, randomized, open-label clinical trial. Integr Cancer Ther. 2012;11(3):204-211.
  • Pillai AK, Sharma KK, Gupta YK, Bakhshi S. Anti-emetic effect of ginger powder versus placebo as an add-on therapy in children and young adults receiving high emetogenic chemotherapy. Pediatr Blood Cancer. 2011;56(2):234-238.
  • Niesler B., „Ginger and its pungent constituents non-competitively inhibit activation of human recombinant and native 5-HT3 receptors of enteric neurons“, Neurogastroenterology & Motility, Volume 25, Issue 5, pages 439-e302, May 2013.

Pfefferminze

  • Walstab J. et al. : Natural compounds boldine and menthol are antagonists of human 5-HT3 receptors: implications for treating gastrointestinal disorders. Neurogastroenterol Motil (2014) 26, 810–820

Entzündung der Mundschleimhaut (Mukositis/Stomatitis)

Mundspüllösung auf Basis OPC Traubenkernextrakt

  • Holzhauer P et al. Prophylaxe der Chemotherapie-assoziierten Mukositis. Deutsche Zeitschrift für Onkologie 36 2015; 47:36-40

Hanföl/Ölziehkur

  • Naseem M. et al. Oil pulling and importance of traditional medicine in oral health maintenance; Int J Health Sci (Qassim). 2017 Sep-Oct;11(4):65-70.
  • Gbinigie O. et al. Effect of oil pulling in promoting oro dental hygiene: A systematic review of randomized clinical trials; Complement Ther Med. 2016 Jun;26:47-54. doi: 10.1016/j.ctim.2016.02.011. Epub 2016 Feb 20.

Fatigue

Guarana

  • Heckman MA, Weil J, Gonzalez de Mejia E. Caffeine (1, 3, 7-trimethylxanthine) in foods: a comprehensive review on consumption, functionality, safety, and regulatory matters. Journal of food science. 2010 Apr;75(3):R77-87. PubMed PMID: 20492310.
  • de Oliveira Campos MP, Riechelmann R, Martins LC, Hassan BJ, Casa FB, Del Giglio A. Guarana (Paullinia cupana) improves fatigue in breast cancer patients undergoing systemic chemotherapy. Journal of alternative and complementary medicine. 2011 Jun;17(6):505-12. PubMed PMID: 21612429 (https://www.ncbi.nlm.nih.gov/pubmed/21612429)
  • da Costa Miranda V, Trufelli DC, Santos J, Campos MP, Nobuo M, da Costa Miranda M, et al. Effectiveness of guarana (Paullinia cupana) for postradiation fatigue and depression: results of a pilot double-blind randomized study. Journal of alternative and complementary medicine. 2009 Apr;15(4):431-3. PubMed PMID: 19388866 (https://www.ncbi.nlm.nih.gov/pubmed/19388866)

Maca

  • Gustavo F. Gonzales: Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands, In: Evidence-Based Complementary and Alternative Medicine, Volume 2012, 2012, Article ID 193496, 10 Seiten: Volltext online. doi:10.1155/2012/193496
  • Gonzales-Arimborgo C. et al. Acceptability, Safety and Efficacy of Oral Administration of Extracts of Black or Red Maca (Lepidium meyenii) in Adult Human Subjects; a randomized, double-blind, placebo-controlled study. Pharmaceuticals 2016,9,49; doi;10.3390

Vitamin Q10

Hand-Fuß-Syndrom

Hanföl

  • Koula-Jenik H et al. Anwendungsbeobachtung zum präventiven Potenzial von Hanföl beim Capecitabin-induzierten Hand-Fuß-Syndrom. Deutsche Zeitschrift für Onkologie 42:80-84,2010

Harnstoff

  • S3 Leitlinie Supportive Therapie bei onkologischen PatientInnen, Leitlinienprogramm der Dt. Krebsgesellschaft; Stand 12.1.18; https://www.leitlinienprogramm-onkologie.de/leitlinien/supportive-therapie/

OPC Traubenkernextrakt

  • Nassiri-Asl M., Hosseinzadeh H., Review of the pharmacological effects of Vitis vinifera (Grape) and its bioactive compounds; Phytother Res. 2009 Sep;23(9):1197-204
  • Katiyar SK, Grape seed proanthocyanidines and skin cancer prevention: inhibition of oxidative stress and protection of immune system; Mol Nutr Food Res. 2008 Jun;52 Suppl 1:S71-6.
  • Khanna S. et al. UPREGULATION OF OXIDANT-INDUCED VEGF EXPRESSION IN CULTURED KERATINOCYTES BY A GRAPE SEED PROANTHOCYANIDIN EXTRACT; Free Radical Biology & Medicine, Vol. 31, No. 1, pp. 38–42, 2001
  • Khanna S. et al. DERMAL WOUND HEALING PROPERTIES OF REDOX-ACTIVE GRAPE SEED PROANTHOCYANIDINS; Free Radical Biology & Medicine, Vol. 33, No. 8, pp. 1089–1096, 2002

Mundsoor

  • Alalwan H. et al. The Anti-Adhesive Effect of Curcumin on Candida albicans Biofilms on Denture Materials, .Front Microbiol. 2017 Apr 20;8:659
  • C. V. B. Martins et al. Curcumin as a promising antifungal of clinical interest, Journal of Antimicrobial Chemotherapy (2009) 63, 337–339
  • Mohamed SIA et al. Naturally occurring immunomodulators with antitumor activity: An insight on their mechanisms of action, Int Immunopharmacol. 2017 Sep;50:291-304 (https://www.ncbi.nlm.nih.gov/pubmed/28734166

Mundtrockenheit

Ananas/Bromelain

  • Mohamed SIA et al. Naturally occurring immunomodulators with antitumor activity: An insight on their mechanisms of action, Int Immunopharmacol. 2017 Sep;50:291-304

Mundspüllösung auf Basis OPC Traubenkernextrakt

  • Holzhauer P et al Prophylaxe der Chemotherapie-assoziierten Mukositis. Deutsche Zeitschrift für Onkologie 36 2015; 47:36-40

Lektin Enzym Gemisch

  • Beuth J: Evidence-based complementary ocology. Anticancer Res.30:1767-1771, 2010
  • Uhlenbruck G et al. Reduced side effects of adjuvant hormone therapy in breast cancer patients by complementary medicine. In vivi 24:799-802,2010

Schädigung des Nervensystems/PNP

Hanföl/Ölziehkur

  • Maroon J. Bost J. Review of the neurological benefits of phytocannabinoids; Surg Neurol Int. 2018; 9: 91.

Vitamin D Mangel

  • Gupta D., Vashi P. : Prevalence of serum vitamin D deficiency and insufficiency in cancer: Review of the epidemiological literature; Experimental and Therapeutic Medicine 2: 181-193, 2011
  • Zeeb H, Greinert R: Bedeutung von Vitamin D in der Krebsprävention. Dtsch. Aerztebl. 107; 638-643 (2010).
  • Bittenbring et al.: Vitamin D Deficiency Impairs Rituximab-Mediated Cellular Cytotoxicity and Outcome of Patients With Diffuse Large B-Cell Lymphoma Treated With but Not Without Rituximab J Clin Oncol 32:3242-3248